Tubulin and Microtubules

Tubulin is one of the components found in the family of globular proteins. It constitutes proteins that make up the microtubules. Microtubules are, on the other hand, intracellular organelles that are formed by the tubulin proteins. These organelles have a wide and important role to play in the body ranging from chromosomes segregation, transport, motility and maintenance of the cell shapes.

Tubulin and microtubules contribute to the development of cancer. This is informed by the fact that in the treatment of cancer, taxol and tesetaxel drugs administered, and the anti- gout agent colchicines bind to tubulin thereby inhibiting the formation of microtubules (Pazdur, 2009). This inhibits neutrophil motility and decreases inflammation. Griseofulvin, an antifungal drug, targets microtubule formation and has applications in the treatment of cancer.

These important structures in the body can be targets of cancer therapies. When the levels of these structures are left to soar unnecessarily, they become a threat to health, since they increase the chances of an individual contracting cancer. This information is based on the reason that anti-cancer drugs only inhibit the formation of microtubules (Tannock, 2005). This means that the body requires only appropriate levels of the protein organelles and any excessive ones would compromise the body’s health.

Tubulin and microtubules are without doubt vital structures in the body. The maintenance of optimal levels is critical, since, based on above discussion, it has been revealed that excess of the organelles forms favorable grounds for cancer development. It is important to check their levels as a way of controlling the cancer disease. This would ensure good health and the proper body functioning.